Rob MacIsaac served as the first Chair of Metrolinx, occupying the position on a full time basis from 2006 to 2009, during which time he oversaw the start-up of the organization and the development and adoption of the Greater Toronto and Hamilton Area's first ever regional transportation plan - The Big Move.

In early 2009, Rob MacIsaac became the 7th President of Mohawk College in Hamilton. He continues his role as Chair of Metrolinx.

From 1997 until 2006, he was the Mayor of the City of Burlington. Prior to this, Mr. MacIsaac was Councillor for the City of Burlington and the Region of Halton, Managing Partner at MacIsaac and Associates, and a lawyer at Goodman and Goodman. He has been heavily involved in the development of Provincial policies for the Greater Golden Horseshoe, serving as Chair of both the Greenbelt Taskforce and the Strategic Planning Sub-panel of the Central Ontario Smart Growth Panel.

Mr. MacIsaac holds a Bachelor of Arts in Economics from the University of Waterloo and a Bachelor of Laws from the University of Western Ontario.